G17R (p.Gly17Arg) variant of DRD4 (D(4) dopamine receptor)
G17R (p.Gly17Arg) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- TOPMed rs1004471672
- gnomAD rs1004471672
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.03
- AlphaMissense 0.20
- MetaLR 0.12
- MetaSVM -1.03
- CADD 16.80
- PolyPhen-2 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available