G17E (p.Gly17Glu) variant of DRD4 (D(4) dopamine receptor)
G17E (p.Gly17Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G17E (p.Gly17Glu) variant details
- p.Gly17Glu
- TOPMed rs1016692423
- gnomAD rs1016692423
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.05
- AlphaMissense 0.08
- MetaLR 0.08
- MetaSVM -1.00
- CADD 8.89
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available