G15W (p.Gly15Trp) variant of DRD4 (D(4) dopamine receptor)
G15W (p.Gly15Trp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
G15W (p.Gly15Trp) variant details
- p.Gly15Trp
- gnomAD 11-637347-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.26
- MetaLR 0.32
- MetaSVM -0.74
- CADD 23.30
- PolyPhen-2 0.83
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available