G15R (p.Gly15Arg) variant of DRD4 (D(4) dopamine receptor)
G15R (p.Gly15Arg) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
G15R (p.Gly15Arg) variant details
- p.Gly15Arg
- gnomAD 11-637347-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.20
- MetaLR 0.11
- MetaSVM -1.05
- CADD 21.00
- PolyPhen-2 0.37
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available
- Literature evidence available