G15E (p.Gly15Glu) variant of DRD4 (D(4) dopamine receptor)
G15E (p.Gly15Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G15E (p.Gly15Glu) variant details
- p.Gly15Glu
- TOPMed rs1858080741
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.06
- AlphaMissense 0.10
- MetaLR 0.10
- MetaSVM -1.02
- CADD 7.28
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 4.4e-05)
- Structural context available