G11E (p.Gly11Glu) variant of DRD4 (D(4) dopamine receptor)
G11E (p.Gly11Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G11E (p.Gly11Glu) variant details
- p.Gly11Glu
- TOPMed rs1274249349
- gnomAD rs1274249349
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.07
- AlphaMissense 0.09
- MetaLR 0.13
- MetaSVM -1.06
- CADD 9.38
- PolyPhen-2 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available