D8Y (p.Asp8Tyr) variant of DRD4 (D(4) dopamine receptor)
D8Y (p.Asp8Tyr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
D8Y (p.Asp8Tyr) variant details
- p.Asp8Tyr
- gnomAD 11-637326-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.14
- MetaLR 0.18
- MetaSVM -0.92
- CADD 21.90
- PolyPhen-2 0.39
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available