D8N (p.Asp8Asn) variant of DRD4 (D(4) dopamine receptor)
D8N (p.Asp8Asn) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
D8N (p.Asp8Asn) variant details
- p.Asp8Asn
- TOPMed rs1220195801
- gnomAD rs1220195801
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.10
- AlphaMissense 0.14
- MetaLR 0.15
- MetaSVM -1.04
- CADD 20.90
- PolyPhen-2 0.01
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available