D8H (p.Asp8His) variant of DRD4 (D(4) dopamine receptor)
D8H (p.Asp8His) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
D8H (p.Asp8His) variant details
- p.Asp8His
- TOPMed rs1220195801
- gnomAD rs1220195801
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.16
- AlphaMissense 0.16
- MetaLR 0.17
- MetaSVM -0.95
- CADD 17.00
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available