D8G (p.Asp8Gly) variant of DRD4 (D(4) dopamine receptor)
D8G (p.Asp8Gly) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
D8G (p.Asp8Gly) variant details
- p.Asp8Gly
- gnomAD rs1564911613
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.10
- AlphaMissense 0.06
- MetaLR 0.18
- MetaSVM -0.99
- CADD 17.80
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available