D10N (p.Asp10Asn) variant of DRD4 (D(4) dopamine receptor)
D10N (p.Asp10Asn) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
D10N (p.Asp10Asn) variant details
- p.Asp10Asn
- gnomAD 11-637332-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.10
- MetaLR 0.15
- MetaSVM -1.01
- CADD 12.20
- PolyPhen-2 0.04
- SIFT 0.38
- Most common in the South Asian population (allele frequency 3.4e-05)
- Structural context available
- Literature evidence available