D10E (p.Asp10Glu) variant of DRD4 (D(4) dopamine receptor)
D10E (p.Asp10Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
D10E (p.Asp10Glu) variant details
- p.Asp10Glu
- TOPMed rs12720386
- gnomAD rs12720386
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.06
- AlphaMissense 0.09
- MetaLR 0.11
- MetaSVM -1.05
- CADD 1.00
- PolyPhen-2 0.00
- Most common in the East Asian population (allele frequency 4.1e-05)
- Structural context available