A9S (p.Ala9Ser) variant of DRD4 (D(4) dopamine receptor)
A9S (p.Ala9Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A9S (p.Ala9Ser) variant details
- p.Ala9Ser
- gnomAD 11-637329-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.12
- MetaLR 0.14
- MetaSVM -0.96
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 0.61
- Population evidence available
- Structural context available
- Literature evidence available