A7V (p.Ala7Val) variant of DRD4 (D(4) dopamine receptor)
A7V (p.Ala7Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A7V (p.Ala7Val) variant details
- p.Ala7Val
- TOPMed rs1200081739
- gnomAD rs1200081739
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.13
- AlphaMissense 0.12
- MetaLR 0.11
- MetaSVM -1.03
- CADD 12.10
- PolyPhen-2 0.09
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available