A7T (p.Ala7Thr) variant of DRD4 (D(4) dopamine receptor)
A7T (p.Ala7Thr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A7T (p.Ala7Thr) variant details
- p.Ala7Thr
- TOPMed rs1411841186
- gnomAD rs1411841186
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.02
- AlphaMissense 0.09
- MetaLR 0.13
- MetaSVM -1.02
- CADD 13.10
- PolyPhen-2 0.01
- Most common in the Middle Eastern population (allele frequency 0.00034)
- Structural context available