A7S (p.Ala7Ser) variant of DRD4 (D(4) dopamine receptor)
A7S (p.Ala7Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A7S (p.Ala7Ser) variant details
- p.Ala7Ser
- TOPMed rs1411841186
- gnomAD rs1411841186
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.03
- AlphaMissense 0.09
- MetaLR 0.12
- MetaSVM -1.01
- CADD 11.00
- PolyPhen-2 0.10
- Most common in the East Asian population (allele frequency 8.5e-05)
- Structural context available