A28V (p.Ala28Val) variant of DRD4 (D(4) dopamine receptor)
A28V (p.Ala28Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A28V (p.Ala28Val) variant details
- p.Ala28Val
- 1000Genomes rs547677287
- TOPMed rs547677287
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.05
- AlphaMissense 0.11
- MetaLR 0.13
- MetaSVM -1.02
- CADD 12.40
- PolyPhen-2 0.01
- Most common in the Non-Finnish European population (allele frequency 8.9e-06)
- Structural context available