A28S (p.Ala28Ser) variant of DRD4 (D(4) dopamine receptor)
A28S (p.Ala28Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
A28S (p.Ala28Ser) variant details
- p.Ala28Ser
- gnomAD 11-637386-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.06
- MetaLR 0.11
- MetaSVM -1.05
- CADD 5.25
- PolyPhen-2 0.00
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available