A28G (p.Ala28Gly) variant of DRD4 (D(4) dopamine receptor)
A28G (p.Ala28Gly) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A28G (p.Ala28Gly) variant details
- p.Ala28Gly
- 1000Genomes rs547677287
- TOPMed rs547677287
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.05
- AlphaMissense 0.06
- MetaLR 0.15
- MetaSVM -1.00
- CADD 10.30
- SIFT 0.21
- Most common in the 1KG:BEB population (allele frequency 0.0052)
- Structural context available