A26W (p.Ala26Trp) variant of DRD4 (D(4) dopamine receptor)

Name: DRD4 A26W (p.Ala26Trp) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-19
License: https://catvariant.com/terms-of-use

A26W (p.Ala26Trp) in DRD4 (D(4) dopamine receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.

A26W (p.Ala26Trp) variant details

p.Ala26Trp
gnomAD 11-637373-TGCGGGG
Frameshift
Variant Prioritization Score for Impact Estimate 0.236
CADD 21.90
Most common in the Non-Finnish European population (allele frequency 1.2e-06)
Structural context available
Literature evidence available