A26S (p.Ala26Ser) variant of DRD4 (D(4) dopamine receptor)
A26S (p.Ala26Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A26S (p.Ala26Ser) variant details
- p.Ala26Ser
- TOPMed rs1296550152
- gnomAD rs1296550152
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.13
- AlphaMissense 0.07
- MetaLR 0.08
- MetaSVM -1.04
- CADD 0.82
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available