A24V (p.Ala24Val) variant of DRD4 (D(4) dopamine receptor)
A24V (p.Ala24Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A24V (p.Ala24Val) variant details
- p.Ala24Val
- TOPMed rs1203166260
- gnomAD rs1203166260
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.11
- AlphaMissense 0.10
- MetaLR 0.10
- MetaSVM -1.01
- CADD 8.48
- PolyPhen-2 0.20
- Most common in the African/African-American population (allele frequency 4.1e-05)
- Structural context available