A24T (p.Ala24Thr) variant of DRD4 (D(4) dopamine receptor)
A24T (p.Ala24Thr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A24T (p.Ala24Thr) variant details
- p.Ala24Thr
- TOPMed rs1858083195
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.05
- AlphaMissense 0.08
- MetaLR 0.11
- MetaSVM -1.00
- CADD 6.55
- PolyPhen-2 0.19
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available