A22V (p.Ala22Val) variant of DRD4 (D(4) dopamine receptor)
A22V (p.Ala22Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A22V (p.Ala22Val) variant details
- p.Ala22Val
- gnomAD rs1451868738
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.06
- AlphaMissense 0.09
- MetaLR 0.13
- MetaSVM -1.01
- CADD 8.34
- PolyPhen-2 0.01
- Most common in the East Asian population (allele frequency 5.2e-05)
- Structural context available