A20V (p.Ala20Val) variant of DRD4 (D(4) dopamine receptor)
A20V (p.Ala20Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A20V (p.Ala20Val) variant details
- p.Ala20Val
- gnomAD rs998551458
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.07
- AlphaMissense 0.12
- MetaLR 0.12
- MetaSVM -1.04
- CADD 10.30
- PolyPhen-2 0.04
- Most common in the South Asian population (allele frequency 0.00024)
- Structural context available