A19T (p.Ala19Thr) variant of DRD4 (D(4) dopamine receptor)
A19T (p.Ala19Thr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A19T (p.Ala19Thr) variant details
- p.Ala19Thr
- gnomAD 11-637359-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.04
- MetaLR 0.12
- MetaSVM -1.03
- CADD 10.20
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available