A19S (p.Ala19Ser) variant of DRD4 (D(4) dopamine receptor)
A19S (p.Ala19Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A19S (p.Ala19Ser) variant details
- p.Ala19Ser
- gnomAD 11-637359-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -1.02
- CADD 7.33
- PolyPhen-2 0.00
- SIFT 0.78
- Population evidence available
- Structural context available
- Literature evidence available