A19P (p.Ala19Pro) variant of DRD4 (D(4) dopamine receptor)
A19P (p.Ala19Pro) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A19P (p.Ala19Pro) variant details
- p.Ala19Pro
- gnomAD rs1858081781
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.06
- AlphaMissense 0.08
- MetaLR 0.15
- MetaSVM -1.01
- CADD 12.80
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available