A19D (p.Ala19Asp) variant of DRD4 (D(4) dopamine receptor)
A19D (p.Ala19Asp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
A19D (p.Ala19Asp) variant details
- p.Ala19Asp
- TOPMed rs1406033786
- gnomAD rs1406033786
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.04
- AlphaMissense 0.07
- MetaLR 0.10
- MetaSVM -1.02
- CADD 0.64
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available