A14S (p.Ala14Ser) variant of DRD4 (D(4) dopamine receptor)
A14S (p.Ala14Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
A14S (p.Ala14Ser) variant details
- p.Ala14Ser
- gnomAD 11-637344-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -0.98
- CADD 19.90
- PolyPhen-2 0.69
- SIFT 0.27
- Population evidence available
- Structural context available
- Literature evidence available