A14D (p.Ala14Asp) variant of DRD4 (D(4) dopamine receptor)
A14D (p.Ala14Asp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A14D (p.Ala14Asp) variant details
- p.Ala14Asp
- gnomAD 11-637345-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.21
- MetaLR 0.24
- MetaSVM -0.87
- CADD 14.10
- PolyPhen-2 0.92
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available