Y88F (p.Tyr88Phe) variant of DRD3 (Dopamine receptor D3)
Y88F (p.Tyr88Phe) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
Y88F (p.Tyr88Phe) variant details
- p.Tyr88Phe
- gnomAD rs1303502710
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- REVEL 0.76
- ESM-1b 1.00
- AlphaMissense 0.14
- MetaLR 0.56
- MetaSVM 0.25
- CADD 27.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available