Y88C (p.Tyr88Cys) variant of DRD3 (Dopamine receptor D3)
Y88C (p.Tyr88Cys) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
Y88C (p.Tyr88Cys) variant details
- p.Tyr88Cys
- gnomAD rs1303502710
- Missense
- Variant Prioritization Score for Impact Estimate 0.758
- REVEL 0.82
- ESM-1b 1.00
- AlphaMissense 0.72
- MetaLR 0.60
- MetaSVM 0.33
- CADD 29.60
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available