Y66H (p.Tyr66His) variant of DRD3 (Dopamine receptor D3)
Y66H (p.Tyr66His) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
Y66H (p.Tyr66His) variant details
- p.Tyr66His
- gnomAD rs1318970010
- Missense
- Variant Prioritization Score for Impact Estimate 0.814
- REVEL 0.93
- ESM-1b 1.00
- AlphaMissense 0.67
- MetaLR 0.66
- MetaSVM 0.54
- CADD 28.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available