Y66C (p.Tyr66Cys) variant of DRD3 (Dopamine receptor D3)
Y66C (p.Tyr66Cys) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
Y66C (p.Tyr66Cys) variant details
- p.Tyr66Cys
- TOPMed rs1381539305
- gnomAD rs1381539305
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- REVEL 0.88
- ESM-1b 1.00
- AlphaMissense 0.42
- MetaLR 0.57
- MetaSVM 0.24
- CADD 28.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available