W96* (p.Trp96Ter) variant of DRD3 (Dopamine receptor D3)
W96* (p.Trp96Ter) in DRD3 (Dopamine receptor D3) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes structural context.
W96* (p.Trp96Ter) variant details
- p.Trp96Ter
- rs867402333
- NCI-TCGA Cosmic COSV9987
- cosmic curated COSV99879
- Ensembl rs867402333
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.831
- AlphaMissense 0.99
- MetaLR 0.76
- MetaSVM 0.84
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.81
- UniProt: Variant assessed as somatic; high impact.
- Structural context available