W85R (p.Trp85Arg) variant of DRD3 (Dopamine receptor D3)
W85R (p.Trp85Arg) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
W85R (p.Trp85Arg) variant details
- p.Trp85Arg
- TOPMed rs1158103384
- gnomAD rs1158103384
- Missense
- Variant Prioritization Score for Impact Estimate 0.77
- REVEL 0.87
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.55
- MetaSVM 0.24
- CADD 29.70
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available