V87A (p.Val87Ala) variant of DRD3 (Dopamine receptor D3)
V87A (p.Val87Ala) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
V87A (p.Val87Ala) variant details
- p.Val87Ala
- TOPMed rs1209362835
- gnomAD rs1209362835
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.54
- ESM-1b 1.00
- AlphaMissense 0.67
- MetaLR 0.15
- MetaSVM -0.86
- CADD 27.90
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available