V82L (p.Val82Leu) variant of DRD3 (Dopamine receptor D3)
V82L (p.Val82Leu) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
V82L (p.Val82Leu) variant details
- p.Val82Leu
- NCI-TCGA Cosmic COSV9987
- cosmic curated COSV99879
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.799
- REVEL 0.82
- ESM-1b 1.00
- AlphaMissense 0.96
- MetaLR 0.61
- MetaSVM 0.43
- CADD 25.50
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available