V78M (p.Val78Met) variant of DRD3 (Dopamine receptor D3)
V78M (p.Val78Met) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
V78M (p.Val78Met) variant details
- p.Val78Met
- TOPMed rs960115346
- gnomAD rs960115346
- Missense
- Variant Prioritization Score for Impact Estimate 0.772
- REVEL 0.77
- ESM-1b 1.00
- AlphaMissense 0.89
- MetaLR 0.60
- MetaSVM 0.29
- CADD 26.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available