T80I (p.Thr80Ile) variant of DRD3 (Dopamine receptor D3)
T80I (p.Thr80Ile) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T80I (p.Thr80Ile) variant details
- p.Thr80Ile
- ExAC rs751054980
- gnomAD rs751054980
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.17
- ESM-1b 0.24
- AlphaMissense 0.16
- MetaLR 0.08
- MetaSVM -1.04
- CADD 23.80
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available