T63A (p.Thr63Ala) variant of DRD3 (Dopamine receptor D3)
T63A (p.Thr63Ala) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T63A (p.Thr63Ala) variant details
- p.Thr63Ala
- gnomAD rs1437485782
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.11
- MetaSVM -0.97
- CADD 23.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available