T21I (p.Thr21Ile) variant of DRD3 (Dopamine receptor D3)
T21I (p.Thr21Ile) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
T21I (p.Thr21Ile) variant details
- p.Thr21Ile
- ExAC rs778559103
- gnomAD rs778559103
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.29
- ESM-1b 1.00
- AlphaMissense 0.27
- MetaLR 0.31
- MetaSVM -0.38
- CADD 24.10
- Most common in the East Asian population (allele frequency 7.7e-05)
- Structural context available