T21A (p.Thr21Ala) variant of DRD3 (Dopamine receptor D3)
T21A (p.Thr21Ala) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T21A (p.Thr21Ala) variant details
- p.Thr21Ala
- TOPMed rs1577619524
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.30
- ESM-1b 1.00
- AlphaMissense 0.08
- MetaLR 0.19
- MetaSVM -0.81
- CADD 22.40
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available