T14S (p.Thr14Ser) variant of DRD3 (Dopamine receptor D3)
T14S (p.Thr14Ser) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T14S (p.Thr14Ser) variant details
- p.Thr14Ser
- NCI-TCGA Cosmic COSV5567
- cosmic curated COSV55679
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.14
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.17
- MetaSVM -1.06
- CADD 19.30
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available