S5N (p.Ser5Asn) variant of DRD3 (Dopamine receptor D3)
S5N (p.Ser5Asn) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S5N (p.Ser5Asn) variant details
- p.Ser5Asn
- cosmic curated COSV55679
- TOPMed rs1402088765
- gnomAD rs1402088765
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.19
- MetaSVM -0.88
- CADD 14.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available