S35F (p.Ser35Phe) variant of DRD3 (Dopamine receptor D3)
S35F (p.Ser35Phe) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S35F (p.Ser35Phe) variant details
- p.Ser35Phe
- ExAC rs200245212
- TOPMed rs200245212
- gnomAD rs200245212
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.04
- MetaSVM -1.08
- CADD 21.60
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available