S117T (p.Ser117Thr) variant of DRD3 (Dopamine receptor D3)
S117T (p.Ser117Thr) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
S117T (p.Ser117Thr) variant details
- p.Ser117Thr
- TOPMed rs200269629
- gnomAD rs200269629
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.94
- MetaLR 0.47
- MetaSVM 0.21
- CADD 25.40
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available