R58Q (p.Arg58Gln) variant of DRD3 (Dopamine receptor D3)
R58Q (p.Arg58Gln) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
R58Q (p.Arg58Gln) variant details
- p.Arg58Gln
- 1000Genomes rs201102020
- ExAC rs201102020
- gnomAD rs201102020
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.31
- ESM-1b 1.00
- AlphaMissense 0.15
- MetaLR 0.23
- MetaSVM -0.68
- CADD 22.20
- Most common in the 1KG:PJL population (allele frequency 0.016)
- Structural context available