R27L (p.Arg27Leu) variant of DRD3 (Dopamine receptor D3)
R27L (p.Arg27Leu) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R27L (p.Arg27Leu) variant details
- p.Arg27Leu
- cosmic curated COSV55680
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.04
- MetaSVM -1.05
- CADD 13.40
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available